Aindrila Mukhopadhyay, Ph.D.

Director, Host Engineering

Joint BioEnergy Institute

Physical Biosciences Division

Lawrence Berkeley National Laboratory

Dr. Mukhopadhyay’s interdisciplinary team at Berkeley Lab is studying signaling and stress response in both environmental and engineered organisms. They are part of the ENIGMA project, where their research includes the study of two-component signaling in the model sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough. As part of the Joint BioEnergy Institute, they adopt targeted and systems-biology approaches to elucidate causes of inhibition during fuel/solvent production from lignocellulose using the host microbes such as Escherichia coli and Saccharomyces cerevisiae. They hope to engineer better hosts for metabolite production and develop tools that are universally useful for microbial cellular engineering. Recently they have also become interested in studying signaling and response in cyanobacteria that dominate desert soil crusts.

http://openwetware.org/wiki/User:Aindrila_Mukhopadhyay

1. What inspires you to work in STEM?

I'm not sure I would call it inspiration. Sometimes you just keep following along the one subject you seem to understand a little better than others. For me that happened when we started chemistry in high school. I had a great tutor, a chemistry graduate student in a local university himself, who encouraged my interest in chemistry. Eventually, chemistry led to microbiology. It was the fun of trying to understand complex systems at a molecular level. So I would say that chemistry was the inspiration for my microbiology career in STEM.

2. What excites you about your work at the Energy Department/Berkeley Lab?

The connectedness of Berkeley Lab's (and that of the DOE) research to the largest, most pressing needs of our times makes for powerful inspiration. To be able to use one's skills, training, and passion for research towards solving even a small part of a big puzzle that will help with issues such as energy and sustainability is very exciting. The opportunities to collaborate with stellar scientists in a wide range of areas have also been one of biggest advantages of being a scientist at Berkeley Lab.

3. How can our country engage more women, girls, and other underrepresented groups in STEM?

My early education was in India. However, perhaps many of the underlying issues may be the same. Support and encouragement in early years are important. Dispelling myths about what a young girl can or cannot be good at are also key. Later on in our careers it is important to know that there is parity in compensation, career advancement, and recognition -- not just between men and women, but also between STEM and other career tracks. Wholehearted support for scientists who are also parents (both men and women) in young families can play an incredibly important role in retaining women in STEM careers.

4. Do you have tips you would recommend for someone looking to enter your field of work?

Start early. There are many opportunities at local, state, and private colleges and universities (and national labs) in the form of training internships, competitions, and participation programs. It’s a good place to figure out which aspect of a science project resonates best with your aptitude. It is easier to position yourself better, later on.

5. When you have free time, what are your hobbies?

I occasionally sketch. Mostly outdoor in my neighborhood (the Mission in San Francisco) and sometimes I go as far as to add some color (watercolor) to the sketch if I've had the sense to draw on good heavy paper. It is very meditative.